el sobretodo - overcoat, overalls
  el sobrino, la sobrina - nephew, niece
  la solapa - lapel; flap of a book or envelope
  la semejanza - similarity, likeness, resemblance
  el sabihondo, la sabihonda, el sabiondo, la sabionda - know-it-all, someone who knows...
  el susto - fright, scare
  salomónico - fair, equitable, wise, just
  el salpicadero - vehicle dashboard
  la salsa - sauce, gravy, salad dressing, salsa...
  la salvaguarda, la salvaguardia - safeguard, protection, security, backup
  sanativo - health-promoting, curative, healing
  el sapo - toad
  la salchicha - sausage
  el secador, la secadora - dryer (the feminine form,...
  el saturnismo - lead poisoning
  el sudor - sweat, perspiration
  la salvajada - atrocity, an act of savagery, travesty
  el silbato - whistle
  el semestre - six-month period, half a year, semester
  la sidra - cider (usually alcoholic)